However, secondary endpoints of the TROPION-Breast01 continue to support a potential benefit of the antibody-drug conjugate in previously treated patients

The reduced efficacy compared to the first-line standard of care led to the termination of the SKYSCRAPER-06 study

Despite being active in this disease setting, the antibody-drug conjugate was associated to high rates of neutropenic complications

Different combinations of immunotherapy agent and radiotherapy or chemoradiotherapy were tested in some patient populations in two studies 

Study confirms favourable safety profiles and encouraging efficacy of an anti-claudin 18.2 antibody-drug conjugate

Efficacy and safety of telisotuzumab adizutecan was investigated in patients with EGFR wild type non-squamous disease

The combination therapy with the CDK 4/6 inhibitor improved overall response rate compared to standard treatment

Strategies to target MTAP deletion, KRAS G12D and ESR1 mutations, and CDK4 and CDK2 further expand the landscape of precision oncology

Data from studies presented highlight the importance of integrating and incorporating comprehensive genomic profiling into clinical practice across a broad range of tumour types