Opinions

For adolescents and young adults with cancer, individualised care that addresses their unique medical and psychosocial needs is essential to improving outcomes and quality of life

Computational models can overcome current limitations of 3D analysis of tumour samples

Extensive research is focusing on the development of tools that may enhance drug development and personalised oncology in the near future

Novel strategies are offering the possibility of extended patient survival and durable disease control

Precision targeting, immune modulation and rational trial design are converging to improve patient outcomes 

While early-phase findings confirm the efficacy and mild toxicity of radiopharmaceuticals, patient selection and logistical issues limit their integration into broad clinical practice

Recent research shows that molecular monitoring is key to identify a patient-tailored window of opportunity for rechallenge

Although the benefits of exercise in patients with cancer are now well established, barriers to an effective integration of physical activity into cancer care remain

Although genomics-guided personalised cancer vaccines have demonstrated efficacy in early-phase clinical studies, we are still awaiting the results of larger-scale trials

Interest is growing rapidly in the field of oncology in the anti-obesity drug target that has recently been investigated in large retrospective studies and preclinical models