Will AI reshape breast cancer screening?
While AI tools have shown promise in reducing false positives and aiding radiologists, large prospective trials are now exploring how technology should be integrated in screening programmes
ESMO BREAST CANCER 2025
Promising early results for emiltatug ledadotin in heavily pretreated triple-negative breast cancer
Phase 1 trial data highlights preliminary efficacy and manageable safety of B7-H4–targeted antibody-drug conjugate in women receiving at least one prior topoisomerase-1 ADC
Study findings refine the use of ctDNA to track resistance to endocrine therapy in advanced breast cancer
A timing window for testing ESR1 mutations in the blood was identified
TILs show value in predicting relapse risk in TNBC
Retrospective data suggest that patients with low baseline TILs and nodal involvement have poor prognosis despite achieving pathological complete response
AI & DIGITAL ONCOLOGY
AI is transforming cancer diagnosis, but systemic barriers still hold it back
A new ESMO systematic review maps AI’s growing role in pathology and oncology, as well as challenges in its implementation due to infrastructure, regulatory framework and human factors
AI applications in oncology go beyond clinical practice
While many models and tools are designed to support clinical decision-making, AI is already serving cancer research for background tasks, with some potential to educate patients too
Can AI and liquid biopsies take precision oncology to the next level?
According to the 2025 ESMO TAT Honorary Awardee, Prof. Philippe Bedard, new technologies have the potential to increase the wealth of information generated from trials and registries
OTHER NEWS
Research offers novel insights to refine first-line treatment in GEP-NETs
Data from new clinical trials reported positive results of radioligand therapy over everolimus and sunitinib, and explore the combination of everolimus and somatostatin analogues
An ESMO roadmap for implementing molecular tumour boards
Newly released recommendations address key areas to facilitate the integration of precision oncology in clinical practice
Peters: “Leadership can be isolating, especially for women”
In a video series produced by the ESMO Women for Oncology, Solange Peters reflects on her career and the leadership challenges she has faced
OPINIONS
Shaping the future for young women facing breast cancer
Ann Partridge
Who benefits from immunotherapy for breast cancer?
Sherene Loi
What is the role of adjuvant immunotherapy in contemporary melanoma care?
Marco Donia
Drug de-escalation in lung cancer: are we nearly there yet?
Benjamin Besse
Tumour-agnostic drug development is revolutionising precision oncology
Vivek Subbiah
OPINIONS
Shaping the future for young women facing breast cancer
Ann Partridge
Who benefits from immunotherapy for breast cancer?
Sherene Loi
What is the role of adjuvant immunotherapy in contemporary melanoma care?
Marco Donia
Drug de-escalation in lung cancer: are we nearly there yet?
Benjamin Besse
Tumour-agnostic drug development is revolutionising precision oncology
Vivek Subbiah