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HER2+ breast cancer: from no hope to good prognosis in 20 years

HER2+ breast cancer: from no hope to good prognosis in 20 years

Trastuzumab has transformed the prognosis for women with HER2+ breast cancer. On the occasion of the ESMO Breast Cancer Virtual Congress 2021, leading oncology experts recall with enthusiasm the pioneering work of researchers like José Baselga in this field and push for continuous research to investigate how to further improve the treatment of this cancer sub-type

What role for real-world evidence in cancer research?

What role for real-world evidence in cancer research?

With the growing use of real-world evidence (RWE) to support regulatory approvals of new anti-cancer medicines in Europe and the USA, can this type of research ensure greater inclusion of women, the elderly, diverse ethnic groups, those with rare cancers and other under-represented populations in oncology studies?

Cancer vaccination: a new era of innovation

Cancer vaccination: a new era of innovation

Promising results with cancer vaccines based on specific antigen mutations in individual tumours, and typically used in combination with checkpoint inhibitors, are fuelling an upsurge of interest in cancer vaccination for patients with established cancer, explains Prof. Pedro Romero. 

There is a growing place for real-world evidence in medical journals

There is a growing place for real-world evidence in medical journals

However, researchers’ concerns about missing opportunities to publish their real-world evidence-based papers in high-ranked scientific journals are justified to some extent due to lack of ‘best practices’ from publishers and suitable peer reviewers for these study designs

Increased bureaucracy downgrades efficiency in cancer research

Increased bureaucracy downgrades efficiency in cancer research

Nearly 20 years since the first steps to harmonise clinical trial regulations across Europe, bureaucracy is now stifling research in oncology. A newly established ESMO Clinical Research Observatory (ECRO) Task Force identifies priorities for action.

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