COLUMNS
Redispensing cancer medicines means caring for the environment
Some initiatives show that collection and distribution of unused medicines can help tackle drug waste, with a potential impact on emissions associated to oncology therapies
The expanding toolbox for immuno-oncology
Novel treatment approaches show encouraging early results in solid tumours, but ways to boost precision immunotherapy are needed
Off-label use of cancer medicines: an option not without challenges
Together with an off-trial use and off-track access to oncology therapies, a consolidated trend is reported in clinical practice despite the uncertainties on efficacy and safety
FROM MAP 2024
Studies present a wider application of sequencing techniques for the treatment of cancer
Whole-genome sequencing and single-cell sequencing can provide valuable insights not only in the identification of new therapy targets, but also to assess minimal residual disease and overcome treatment resistance
Data from molecular analyses unveil diverse resistance mechanisms to endocrine therapy in breast cancer
Among the presented findings, a potential role for ESR1 gene fusions was observed
PRECISION ONCOLOGY
Drug Rediscovery Protocol-like Clinical Trials facilitate access to precision oncology
Data from studies presented highlight the importance of integrating and incorporating comprehensive genomic profiling into clinical practice across a broad range of tumour types
Claudin-targeted antibody–drug conjugates are promising treatments for solid tumours
According to results from several phase I trials, this precision oncology strategy also offers manageable safety
Multi-gene ctDNA profiling effectively matches patients with advanced cancer to targeted therapies
In France, a nationwide programme aims to broaden access to the technology based on the positive results collected so far
OPINIONS
Translating cancer genome insights into practical clinical tools
Elli Papaemmanuil
Innovation is leading to a comprehensive ‘map’ of tumours
Joakim Lundeberg
How to bridge the gap between palliative care and oncology?
Rita Canario
Physical activity is beneficial for patients with cancer, but also challenging
Gabriella Pravettoni
Rising rates of cancer in young people: nature or nurture?
Shuji Ogino
ESMO Immuno-Oncology 2024 Congress: an event to explore challenges and emerging trends in the field
All videosOPINIONS
Translating cancer genome insights into practical clinical tools
Elli Papaemmanuil
Innovation is leading to a comprehensive ‘map’ of tumours
Joakim Lundeberg
How to bridge the gap between palliative care and oncology?
Rita Canario
Physical activity is beneficial for patients with cancer, but also challenging
Gabriella Pravettoni
Rising rates of cancer in young people: nature or nurture?
Shuji Ogino