![Yardena Samuels](/var/esmo/storage/images/media/esmo-daily-reporter/images/portraits/yardena-samuels/14684632-1-eng-GB/yardena-samuels_i770.jpg)
New targets for off-the-shelf treatments open up the field of precision immunotherapy
The identification of mutation-derived neoantigens may help elicit antitumour immune responses in patients with cancer, but this approach is challenging
![Chiara Bonini](/var/esmo/storage/images/media/esmo-daily-reporter/images/portraits/chiara-bonini/14684617-1-eng-GB/chiara-bonini_i770.jpg)
Improving the efficacy of engineered T-cells – from gene transfer to genome editing
A new level of sophistication, namely genome editing, is now available to help overcome previous hurdles with adoptive T-cell therapies