Could the daunting biology of small-cell lung cancer provide the key to elucidating drug resistance?
At ELCC 2021, Prof. Fiona Blackhall sees hope for improving patients’ poor prognoses on the horizon
What role for real-world evidence in cancer research?
With the growing use of real-world evidence (RWE) to support regulatory approvals of new anti-cancer medicines in Europe and the USA, can this type of research ensure greater inclusion of women, the elderly, diverse ethnic groups, those with rare cancers and other under-represented populations in oncology studies?
Real-world research does not need to replace randomised clinical trials to be recognised as valuable for treatment evaluation
According to Prof. Urania Dafni, high quality real-world evidence can provide broader information and more generalisable conclusions to verify the clinical applicability of evidence from RCTs
Cancer vaccination: a new era of innovation
Promising results with cancer vaccines based on specific antigen mutations in individual tumours, and typically used in combination with checkpoint inhibitors, are fuelling an upsurge of interest in cancer vaccination for patients with established cancer, explains Prof. Pedro Romero.
There is a growing place for real-world evidence in medical journals
However, researchers’ concerns about missing opportunities to publish their real-world evidence-based papers in high-ranked scientific journals are justified to some extent due to lack of ‘best practices’ from publishers and suitable peer reviewers for these study designs
The secret of a successful academia-industry partnership
This year’s recipient of the TAT Honorary Award Prof. Ruth Plummer, retraces the most significant milestones of her career in early phase studies
